ProSIAmpler

The ProSIAmpler is the world’s newest and most advanced Automated On-line Sampling System that offers substantial time savings for liquid-based processes.

Eliminate offline pre-treatment with a fully integrated online sampling and pre-treatment system prior to LC-MS analysis.

The ProSIAmpler can monitor bioreactors' nutrients, pH, cell densities, and viabilities, in-situ, using ion-selective electrodes (ISE). This unlocks the potentiometric determination of several bioreactor parameters that are essential for optimal conditions where the ProSIAmpler can be programmed to automatically sample upon certain analyte concentrations or pH levels.

  • The ProSIAmpler automates the most complex pretreatment procedures and provides unified, simultaneous, and uninterrupted flow.

    One Platform for Any Integration

    In-line Pretreatment: Diluting, Concentrating, Mixing, Derivatization, Heating and Cooling

    Sampling Solutions: Sample from 1-8 vessels / sample streams. Withdraw cell-free or whole cell samples. Sample line is cleaned and sterilized after every sample.

    Instrument Integrations: Easily integrate to Agilent, Waters, Beckman-Couler, Roche, Nova, Thermo, and many other instrumentation options.

  • ANALYZER
    Type:     Sequential Injection Analyzer
    Enclosure Material: Aluminum (powder-coated / anodized)

    SYRINGE PUMPS

    Type: XCalibur high-precision syringe pump
    Wetted Materials: Glass, Teflon®, PCTFE
    Resolution: 24,000 steps per full stroke
    Speed: 1.2s – 20 min per full stroke

    PERISTALTIC PUMP
    Type:     2-channel peristaltic, common pressure plate
    Materials: Delrin, Stainless Steel
    Tubing Type: Elastic tubing with 1 mm wall thickness
    Flow Rate: 0.5-2.0 mL/min per channel with 1 mm ID tubing
    2.0-8.0 mL/min per channel with 2 mm ID tubing

    VALVE
    Type:     10 port multi-position valve
    Wetted Materials: PPS, Valcon E2, Ultem®, Plexiglas
    Port Type: Flat-bottom ¼-28

    RELAY OUTPUT
    Voltage: 24 V
    Current: Max 4 mA

    DIMENSIONS
    Height: 31 cm / 13.5 in
    Width: 21 cm / 8.3 in
    Depth: 29 cm / 11.5 in
    Weight: 8 kg / 17 lb

    COMMUNICATION
    Type: USB
    Control Options: SIAsoft – FIAlab’s proprietary software

    POWER REQUIREMENTS

    Voltage: 24 V DC
    Current: Man 2.5 A


  • ProSIAmpler Brochure >

    SIAsoft >

  • Image of a ProSIAmpler setup

    Full ProSIAmpler Setup

    ProSIAmpler (R) and ProSIALH (L)

  • ProSIAmpler

    ProSIAmpler with Cover

  • ProSIAmpler setup with covers

    Interlocking covers for front plates

  • SIAlock + Hub

    Pairs with bioreactor to create a sterile barrier for sampling

  • 250CC

    Cell Clarification Cartridge for as little as 250μL

  • ProA Column

    ProteinA Column for in-line purification

  • Peltier Heater & UV-Vis Detection Module

    Peltier Heater

    Peltier Heater & UV-Vis Detection Module

Product Highlights

Automation

Automation

Automate the most complex pre-treatment procedures.

Unified

Unified

Unified, simultaneous and uninterrupted flow achieved.

Sensitivity

Sensitivity

Preconcentrate low titer samples.

Speed

Speed

Protein A in less than 5 minutes.

Request a Quote

If you would like more information or a quote of our products, please email: sales@flowinjection.com
Or, call us at 206-258-2290. One of our expert sales staff will be sure to help you.